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AI Digital Twins Are Helping People Manage Diabetes and Obesity

The Owner Press by The Owner Press
February 18, 2026
in Newswire
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Based mostly on logged meals, the app predicts an individual’s blood sugar response to these meals. It additionally makes personalised suggestions all through the day, reminiscent of adjusting portion measurement, selecting a unique meals mixture, or taking a stroll after consuming. Customers can settle for or ignore these recommendations—possibly broccoli isn’t their favourite meals, or they like to train throughout a selected time of the day. The app makes use of AI to adapt to their preferences over time. Customers may also chat with human coaches if they’ve particular well being questions.

For Buckley, Twin Well being has helped him make more healthy selections, reminiscent of swapping out frozen, prepackaged breakfast sandwiches for home made breakfast burritos with low-carb, high-fiber wraps. He not drinks soda, and he walks a number of miles a day.

“Once I first began this system, I may barely make it a mile earlier than my again was hurting, my knee was hurting. Now I am doing six and a half miles each morning,” he says.

He likes getting immediate suggestions from the app and likewise monitoring his biometrics over time. He can see that his physique fats share and blood strain have been trending downward.

“That is the place I get my motivation to maintain strolling and maintain doing the work,” he says.

Buckley reached his preliminary weight aim of 300 kilos and is now round 275. After being on blood strain treatment for many years, his physician not too long ago steered a decrease dose.

When Twin Well being approached the Cleveland Clinic’s well being plan about utilizing its program, workers endocrinologist Kevin Pantalone was initially skeptical. He determined to conduct a examine himself.

“We’ve got actually struggled to implement way of life modification in a really efficient method. Sufferers typically require quite a few therapies to regulate their diabetes,” he mentioned. “So I used to be definitely very .” Regardless of the age-old recommendation of merely exercising extra and maintaining a healthy diet, most Individuals battle to get the beneficial quantity of weekly bodily exercise and have problem sticking to a nutritious diet.

Pantalone and his colleagues recruited 150 contributors with sort 2 diabetes, randomly assigning 100 folks to the Twin program and the remaining to a management group. On common, contributors have been 58 years previous with weight problems and had a blood glucose degree, or A1C, of seven.2 p.c. A degree of 6.5 p.c or larger signifies diabetes. The aim of the trial was to see if contributors may attain an A1C of lower than 6.5 p.c with fewer drugs.

After 12 months, 71 p.c of the examine contributors utilizing the Twin app achieved that blood sugar degree with fewer drugs, whereas solely 2 p.c of individuals within the management group did. The folks utilizing Twin additionally misplaced extra weight—8.6 p.c of their physique weight versus 4.6 p.c within the management group.

At the start of the examine, 41 p.c of these utilizing Twin have been on a GLP-1 treatment, however by the tip of the examine, solely 6 p.c nonetheless have been. Within the management group, 52 p.c of contributors began off on a GLP-1, and on the finish of the examine that elevated to 63 p.c. The outcomes were published within the New England Journal of Medication Catalyst final yr.



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