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Neurogen Biomarking Virtual Care Ecosystem Cuts Time to Alzheimer’s Intervention by 4.5 Years

The Owner Press by The Owner Press
August 7, 2025
in Business News
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Neurogen Biomarking Virtual Care Ecosystem Cuts Time to Alzheimer’s Intervention by 4.5 Years
Elisabeth Thijssen, PhD, Chief Scientific Officer of Neurogen Biomarking.

What You Ought to Know: 

– Developments in accelerating early Alzheimer’s illness (AD) screening and entry to care, confirmed from three various group pilot initiatives, had been introduced as we speak throughout a podium presentation on the Alzheimer’s Association International Conference® 2025 (AAIC). The research, entitled “Distant Assortment of Biomarkers for Alzheimer’s Illness and Associated Issues,” validated Neurogen’s new ecosystem, which brings collectively the primary in-home blood biomarker testing and a cognitive evaluation with digital care.

– The research findings reveals that this ecosystem has the potential to cut back the time from the earliest improvement of signs to care by 4.5 years, considerably breaking down boundaries to early detection and remedy of Alzheimer’s illness. The research additionally validated a powerful correlation between the TASSO, a non-invasive, needle-free blood assortment technique, and conventional phlebotomist blood draw/capillary assortment, suggesting TASSO’s potential to efficiently triage sufferers.

Pressing Unmet Want for Early AD Detection

An estimated 40% of People aged 65 and older (over 16 million folks) expertise some type of reminiscence impairment. But, fewer than 8% of older adults with Gentle Cognitive Impairment (MCI) ever obtain a proper analysis, leaving 92% with out solutions or entry to early intervention. On common, there’s a staggering 6- to 8-year delay from symptom onset to analysis, although present remedies are handiest within the earliest phases of illness. Additional compounding this, fewer than one in 5 Alzheimer’s diagnoses within the U.S. at present contain biomarker testing as a result of accessibility and scientific experience gaps. These information underscore an pressing name to rework how Alzheimer’s and cognitive decline are detected and managed, particularly because the getting older inhabitants grows.

“Neurogen’s ecosystem is constructed to satisfy the pressing international demand for sooner adoption of breakthrough testing applied sciences for early detection of AD. Our mission is to provide everybody equal entry to cutting-edge expertise to detect Alzheimer’s early—when remedy could make the best influence on the course of individuals’s lives,” mentioned Elisabeth Thijssen, PhD, Chief Scientific Officer, Neurogen Biomarking and the session presenter.

Examine Design and Outcomes

The findings stem from three free group occasions focusing on folks aged 50 and older, held at native hospitals in Chicago, IL; Flint, MI; and Coldwater, MI. Contributors had been recruited by way of group engagement, conventional and social media, and outreach to well being and wellness organizations.

Screening Course of:

  • Contributors started with a sophisticated digital cognitive evaluation and a quick way of life survey.
  • Each participant underwent a conventional IV venous blood draw by a licensed skilled, with the TASSO assortment supplied as an non-obligatory addition.
  • All samples had been preserved through ambient cargo, sustaining integrity with out refrigeration or freezing.
  • IV samples had been analyzed utilizing the ALZpath P-tau217 assay, a validated ultrasensitive biomarker take a look at correlating intently with Alzheimer’s pathology.
  • Testing was carried out in CLIA- and CAP-certified laboratories, making certain scientific accuracy, with outcomes obtainable inside days. Telehealth counseling with a board-certified neurologist was offered for follow-up if wanted.

Key Examine Outcomes (from 455 individuals):

  • Demographics: 66% girls, common age 67, 45% White/Caucasian, 39% Black/African American.
  • Elevated P-tau217: 26% of individuals had elevated P-tau217 concentrations.
  • Cognitive Impairment: 80% confirmed some type of cognitive impairment, aligning with expectations.
  • TASSO Accuracy: TASSO recognized elevated P-tau217 with 88% accuracy, assembly efficiency necessities for AD triaging.
  • Accelerated Intervention: The Neurogen ecosystem decreased the time from cognitive issues to intervention by 4 years—altering the usual time from emergence of issues from 3-6 years to 4 months-1.5 years.
  • Comply with-up Care: Contributors with elevated take a look at outcomes obtained telehealth follow-up care from board-certified neurologists inside days.

Neurogen’s on-line ecosystem gives in-home blood biomarker testing for phosphorylated (p-tau217) and superior digital cognitive testing for folks with reminiscence issues. Outcomes are guided by board-certified neurologists through telehealth. The platform is at present in beta take a look at and getting ready for nationwide launch, providing a possible resolution to satisfy the pressing international demand for sooner adoption and equitable entry to breakthrough testing applied sciences for early detection of AD.



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Tags: AlzheimersBiomarkingcarecutsecosysteminterventionNeurogenTimeVirtualyears
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