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Scientists are finding ways to keep aging brains youthful : NPR

The Owner Press by The Owner Press
July 15, 2025
in Newswire
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The human mind tends to lose a step as we age. Now, scientists wish to decrease that decline by finding out folks with distinctive brains.



JUANA SUMMERS, HOST:

As soon as we get previous about age 40, even a wholesome mind begins to lose a step or two. Response instances get slower. It is tougher to recollect all the things in your buying listing. However scientists are in search of methods to attenuate these modifications. NPR’s Jon Hamilton studies.

JON HAMILTON, BYLINE: Reminiscence lapses and slower considering may be indicators of a illness like Alzheimer’s. However Matt Huentelman of the Translational Genomics Analysis Institute in Phoenix says often they simply imply somebody’s mind is getting older.

MATT HUENTELMAN: Each of these issues, reminiscence and processing velocity, change with age in a standard group of individuals.

HAMILTON: Huentelman ought to know. He helps run MindCrowd, a free on-line cognitive check that is been taken by greater than 700,000 folks of all ages. Huentelman says a couple of thousand of these folks had check scores indicating their mind was distinctive.

HUENTELMAN: The best way that we outline an distinctive mind is somebody who performs at a degree that’s about 30 years youthful than them in relation to a reminiscence check or a processing velocity check.

HAMILTON: Huentelman says good genes are one issue, however he and a workforce of researchers are in search of different variations.

HUENTELMAN: We wish to research these distinctive performers as a result of we predict they will inform us what the remainder of us ought to be doing.

HAMILTON: Early outcomes recommend that sleep and sustaining cardiovascular well being are a great begin. Huentelman was one among a number of dozen researchers who met in Miami this summer time to debate wholesome mind getting old. The occasion was hosted by the McKnight Mind Analysis Basis. One other speaker was Dr. Christian Agudelo, a sleep neurologist on the College of Miami.

CHRISTIAN AGUDELO: I feel the worth of sleep and sleep deprivation grew to become true to me once I had children.

HAMILTON: Agudelo’s children are 4 and 6 now. He says his personal expertise is constant along with his analysis on the connection between sleep and cognitive decline.

AGUDELO: The higher you sleep, the higher your mind well being goes to be, each structurally and functionally.

HAMILTON: Agudelo says the bottom line is getting high-quality sleep, which permits the mind to cycle by way of all of the sleep phases. Researchers can measure how nicely an individual is sleeping by monitoring their brainwave patterns, however Agudelo says folks often know once they’ve had a great evening’s relaxation.

AGUDELO: You fall asleep, you get up and you’re feeling like that have was worthwhile. You are feeling refreshed. And all of us, hopefully, have skilled that.

HAMILTON: Guaranteeing high-quality sleep is difficult, however Agudelo says you possibly can enhance the percentages with sure behaviors.

AGUDELO: Waking up on the identical time each single day and aligning our sleep rhythms with the rhythm of the solar. Being energetic each socially and bodily so we will go to sleep extra simply and extra deeply.

HAMILTON: Dr. Charles DeCarli, a neurologist on the College of California, Davis, says mind getting old can also be affected by vascular threat elements like blood strain, levels of cholesterol and diabetes.

CHARLES DECARLI: We have a tendency to consider them as affecting the center, generally the blood vessels within the legs or stroke, not a lot because it impacts on the mind itself.

HAMILTON: However DeCarli’s analysis on hundreds of individuals 65 and older discovered a robust correlation.

DECARLI: The scale of the mind, the form of the mind, the tissue integrity of the mind appears to be like older in individuals who have these threat elements than those that don’t have them.

HAMILTON: So DeCarli and a workforce of researchers are finding out whether or not it is potential to guard the mind by aggressively treating circumstances that have an effect on the circulatory system.

DECARLI: The query is, you probably have these ailments they usually’re nicely managed, will you’ve a younger-looking mind? And the reply appears to be sure.

HAMILTON: Researchers say different methods to maintain your mind youthful embody avoiding smoking, limiting alcohol and getting a number of train.

Jon Hamilton, NPR Information.

Copyright © 2025 NPR. All rights reserved. Go to our web site terms of use and permissions pages at www.npr.org for additional data.

Accuracy and availability of NPR transcripts might differ. Transcript textual content could also be revised to appropriate errors or match updates to audio. Audio on npr.org could also be edited after its unique broadcast or publication. The authoritative file of NPR’s programming is the audio file.



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